Carnosine and Longevity
research suggests that carnosine has anti-aging potential due to its unique abilities
to protect and extends the functional life of the body's key building blocks,
i.e., cells, proteins, DNA and lipids. Carnosine may be fairly called an agent
of longevity. When that agent is safe, naturally present in the body and in food,
and has demonstrated prolongation of life span in animals and cultured human cells,
it is fundamental to any life extension program.
How does carnosine prolong
We do not yet know the full answer, but carnosine's properties
may point up key mechanisms of tissue and cell aging, as well as the anti-aging
measures that counteract them.
Do carnosine's rejuvenating effects on
cells extend to the entire organism?
Similar anti-senescence effects have
now been demonstrated in mice. A Russian study tested the effect of carnosine
on life span and indicators of senescence in senescence-accelerated mice. Half
the mice were given carnosine in their drinking water starting at two months of
age. Carnosine extended the life span of the treated mice by 20% on average, compared
to the mice not fed carnosine.
Carnosine did not alter the 15 month maximum
life span of the senescence-accelerated mice strain, but it did significantly
raise the number of mice surviving to old age. The mice given carnosine were about
twice as likely to reach the ripe old age of 12 months as untreated
mice. It also improved indicators of senescence measured at the old age
of ten months.